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Home/Authors/Hao Zhou

Hao Zhou

8 indexed papers

Recent (6 mo)
8
With code
0
Influential cites
0
Benchmarked
0

Publications per year

8
26

Top categories

AI×6NLP×3Biomolecules×2Crypto×2Info Retrieval×1Multiagent×1Multimedia×1Sound×1

Frequent co-authors

Keyue Qiu2×
Wei-Ying Ma2×
Qing Wang2×
Hua Dai2×
OneRec Team1×
Biao Yang1×

Research Timeline

2026
PAC-DP: Personalized Adaptive Clipping for Differentially Private Federated Learning

The paper proposes PAC-DP, a personalized adaptive clipping framework that dynamically adjusts gradient clipping thresholds based on the desired privacy budget, significantly improving the privacy-utility trade-off in federated learning.

Safety Anchor: Defending Harmful Fine-tuning via Geometric Bottlenecks

The paper introduces Safety Bottleneck Regularization (SBR), a novel defense mechanism that anchors LLM safety by constraining the unembedding layer, effectively preventing harmful fine-tuning (HFT) even when other defenses fail.

MTAVG-Bench 2.0: Diagnosing Failure Modes of Cinematic Expressiveness in Multi-Talker Audio-Video Generation

The paper introduces MTAVG-Bench 2.0, a new benchmark designed to diagnose high-level failure modes of cinematic expressiveness in multi-talker audio-video generation, showing that even advanced models struggle with complex scene-level failures.

MindZero: Learning Online Mental Reasoning With Zero Annotations

MindZero introduces a self-supervised reinforcement learning framework that trains multimodal large language models (MLLMs) for efficient and robust online mental reasoning without requiring explicit mental state annotations.

AMix-2: Establishing Protein as a Native Modality in Large Language Models

The paper introduces AMix-2, a novel protein-text foundation model that unifies protein understanding and sequence design by embedding both modalities in a shared token space, achieving state-of-the-art performance on comprehensive benchmarks.

UniD$^3$: A Knowledge Graph-Enhanced RAG Framework for Drug-Disease Discovery and Reasoning

UniD$^3$ is a novel Knowledge Graph-enhanced RAG framework that processes vast biomedical literature to systematically extract, organize, and validate comprehensive drug-disease knowledge, achieving high accuracy in structured data generation.

Demystifying Multimodal Biomolecular Co-design With Intrinsic Geodesic Coupling

The paper introduces GeoCoupling, a framework that systematically optimizes the temporal coupling between heterogeneous modalities to improve the co-design of biomolecules, outperforming fixed synchronous coupling methods.

OneReason Technical Report

The paper proposes OneReason, a framework that enhances the reasoning capability of generative recommendation models by focusing on improving item perception and structuring user behavior into coherent latent interests.

Highlighted terms show continued research focus across papers

Papers

cs.IRcs.AIcs.CLRecentJun 4, 2026

OneReason Technical Report

OneRec Team, Biao Yang, Boyang Ding, Chenglong Chu +80 more

The paper proposes OneReason, a framework that enhances the reasoning capability of generative recommendation models by focusing on improving item perception and structuring user behavior into coheren…

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q-bio.BMcs.AIRecentJun 1, 2026

Demystifying Multimodal Biomolecular Co-design With Intrinsic Geodesic Coupling

Keyue Qiu, Xintong Wang, Zhilong Zhang, Hao Zhou +1 more

The paper introduces GeoCoupling, a framework that systematically optimizes the temporal coupling between heterogeneous modalities to improve the co-design of biomolecules, outperforming fixed synchro…

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cs.CLRecentMay 31, 2026

UniD$^3$: A Knowledge Graph-Enhanced RAG Framework for Drug-Disease Discovery and Reasoning

Qing Wang, Tianshi Liu, Minghao Zhou, Jialu Liang +4 more

UniD$^3$ is a novel Knowledge Graph-enhanced RAG framework that processes vast biomedical literature to systematically extract, organize, and validate comprehensive drug-disease knowledge, achieving h…

View →
cs.AIcs.MARecentMay 29, 2026

MindZero: Learning Online Mental Reasoning With Zero Annotations

Shunchi Zhang, Jin Lu, Chuanyang Jin, Yichao Zhou +2 more

MindZero introduces a self-supervised reinforcement learning framework that trains multimodal large language models (MLLMs) for efficient and robust online mental reasoning without requiring explicit…

View →
q-bio.BMcs.AIRecentMay 29, 2026

AMix-2: Establishing Protein as a Native Modality in Large Language Models

Keyue Qiu, Yixin Wu, Lihao Wang, Yawen Ouyang +18 more

The paper introduces AMix-2, a novel protein-text foundation model that unifies protein understanding and sequence design by embedding both modalities in a shared token space, achieving state-of-the-a…

View →
cs.AIcs.MMcs.SDRecentMay 27, 2026

MTAVG-Bench 2.0: Diagnosing Failure Modes of Cinematic Expressiveness in Multi-Talker Audio-Video Generation

Haitian Li, Yanghao Zhou, Heyan Huang, Liangji Chen +14 more

The paper introduces MTAVG-Bench 2.0, a new benchmark designed to diagnose high-level failure modes of cinematic expressiveness in multi-talker audio-video generation, showing that even advanced model…

View →
cs.CRcs.AIcs.CLRecentMay 7, 2026

Safety Anchor: Defending Harmful Fine-tuning via Geometric Bottlenecks

Guoxin Lu, Letian Sha, Qing Wang, Peijie Sun +3 more

The paper introduces Safety Bottleneck Regularization (SBR), a novel defense mechanism that anchors LLM safety by constraining the unembedding layer, effectively preventing harmful fine-tuning (HFT) e…

View →
cs.CRRecentMar 25, 2026

PAC-DP: Personalized Adaptive Clipping for Differentially Private Federated Learning

Hao Zhou, Siqi Cai, Hua Dai, Geng Yang +2 more

The paper proposes PAC-DP, a personalized adaptive clipping framework that dynamically adjusts gradient clipping thresholds based on the desired privacy budget, significantly improving the privacy-uti…

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