Jianan Zhao
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126
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ML×1AI×1
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2026
Plausibility Is Not Prediction: Contrastive Evidence for LLM-Based Cellular Perturbation Reasoning
The paper introduces CORE, a contrastive evidence organization method, which significantly improves the accuracy of LLM-based predictions of gene expression changes following cellular perturbations by reframing the task as a comparison between related conditions.
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Papers
cs.LGcs.AIRecentMay 31, 2026
Plausibility Is Not Prediction: Contrastive Evidence for LLM-Based Cellular Perturbation Reasoning
Xinyu Yuan, Xixian Liu, Jianan Zhao, Yashi Zhang +2 more
The paper introduces CORE, a contrastive evidence organization method, which significantly improves the accuracy of LLM-based predictions of gene expression changes following cellular perturbations by…
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